Tag Archives: GBA

WPC Science Day Two: Genetics Updates

From James Beck, Ph.D., Director of Research Programs Here are some additional scientific updates from this week’s 2nd World Parkinson Congress (WPC). Michael Schlossmacher, M.D., reported the results of his recent experiments that demonstrate that mutations in the GBA gene, which were recently identified as a major risk factor for Parkinson’s disease (PD), actually contribute to an increase in the levels of alpha-synuclein in nerve cells. Alpha-synuclein is the protein that accumulates in dying nerve cells and is the hallmark of Parkinson’s disease. This result provides a biological explanation as to the significance of these GBA mutations and their relevance… read more Read More