Monthly Archives: June 2012

Easing Dyskinesia: PDF-funded Research from 2007 Leads to Testing of Experimental Drug

Earlier this week, PsychoGenics Inc., announced that an experimental drug for Parkinson’s, eltoprazine, seemed to reduce dyskinesia in people with Parkinson’s in early studies.  Dyskinesias are the twisting and writhing movements that occur as PD progresses – a common side effect of the medication levodopa (Sinemet®).    Back in 2007, it was PDF-funded researcher Manolo Carta Ph.D., along with Anders Björklund, M.D., who performed the pre-clinical research that led to the identification of this drug.  At the time, while many researchers were looking at dopamine neurons as the culprit behind dyskinesias (through their interaction with levodopa), Dr. Carta’s proposal suggested something… read more Read More

Happy Birthday to the Original PDF Champion

Parkinson’s Disease Foundation (PDF) would like to recognize the birthday of our founder and the original PDF Champion, Mr. William Black! In 1957, Mr. Black’s, controller and close friend was diagnosed with Parkinson’s disease. Appalled to learn that no truly effective therapy was available, nor was any basic research being conducted on the disease, Mr. Black set up PDF to establish a research program aimed at finding effective drug treatment. He made two major gifts: one to Columbia University to help build the research laboratory with a floor dedicated to Parkinson’s research; the other to endow PDF. Help PDF fulfill Mr. Black’s… read more Read More