Monthly Archives: March 2012

PDF Research Advocates in Action

Last week, Dr. Beck discussed the role of PDF Research Advocates in PDF’s grant review. As he said, “These people, PDF’s Research Advocates, part of the Parkinson’s Advocates in Research program, insure what we will fund is not just the best for science’s sake but for the sake of people too.” Wondering what exactly our PDF Research Advocates do? We want them to tell you in our own words. Last year, PDF was able to steal a few minutes from Research Advocates Becky and Tom, in the midst of grant review. They were kind enough to explain their work in… read more Read More

Grant Review at PDF

Today is a big day for many at PDF — it is our annual grant review. Of course, those most affected by what goes on in the big conference room will not be there. There are two groups who depend on tomorrow’s outcome: the scientists who have given us their best ideas for our scientific advisors to judge and the people who live every day with Parkinson’s and are counting on these great ideas to make a difference in their disease and their lives. I am confident that the team of scientists helping — members of our scientific advisory board… read more Read More

Understanding the FDA Committee’s Decision to Recommend Approval for Neurogenic Orthostatic Hypotension Drug

From James Beck, Ph.D., Director of Research Programs You may have read the recent news about the small pharmaceutical company,Chelsea Therapeutics, and their drug Northera™ (droxidopa). Chelsea recently received the recommendation of a FDA advisory committee to approve droxidopa as a treatment for neurogenic orthostatic hypotension or NOH for short. This recommendation was a big surprise since FDA documents released ahead of the committee meeting showed that agency staff members were clearly against approval; nevertheless, this approval recommendation will strongly influence the final decision expected to be made later this month. What is NOH? Normally, blood pressure increases as you… read more Read More